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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '428a7bc5c9a5adeec658f14d8647cf7111d8d2f69c37e3fdfc0794cd23ec9301' 
  AND token = 'sXF0rgTVSNDJiR+tN0szB6Hu7Gma4rlyVDpe0vdOjxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}