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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77410c1cb2cdbba8d34e4d789c251a5bf7b00f5c887721eb13d6c57f6d25037e' 
  AND token = 't+yoxE6dDvsUcWuPmly8cI3olNFMxdrhlsQ7+VYHSs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}