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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2439202165c7948457bb573be4330770bf341246a98ada2df41e504abb7a5a2' 
  AND token = 'LGeb5x24QvQo1bH1s8dTH6BP2wiZMhBXB9FNQHxwFnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}