SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd386227cfbebc67c53cdc875c563273b7719df7921de916f695ee01267acc00' 
  AND token = 'Z/ycDeZO1XbhQWvmlBKyv/g7mVDRfDG5AoxoZSL9e9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}