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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b001ea08e000213e58c0ec8cb37cc0aa46825d5dccd58200659b7c7c55721ef3' 
  AND token = 'HIO4wBE0ZMVg2CvLP3kvyTfT2Ce+C1UUuQtq3tQDmz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}