SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb87cc621adb7801bf83238cfe336758c7afd0d2d9f94eb5d5d1c5f5e42599a' 
  AND token = 'VcikKMb+BKqAVqXQo2ZcNqVxX2sg+fiTrU7vzUNqmDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}