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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f2f5f42386918378a67cc90d11e0219eafefcbda0a7f1c6b3f7b5b98d499e9f' 
  AND token = 'guQIS/Of6wHAZij1vFvkYwEEiZ4bc7N8+mDmAbE+inY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}