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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0be49fa1a29a4f83efc6acd15e1405063d097653370d7cbce9c6cf92bca180f5' 
  AND token = 'LGtxFC1nyMUMgXxvOOno1tBXFa8pN5W/ePMzrmV8jg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}