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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287f2045b33288f05d4f8c8e01d4fe1e1e6dc34b5570a8038090b3e14139fdfa' 
  AND token = 'TFkzLlB4ufbRFgn89UF9C+ig7EQll0hx8sMWqkjRAQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}