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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c08ec2d8f8cabd6f9142574ff8d1feecac011b8d613e076ec7ac2ca234d3b23' 
  AND token = 'k9R+bRKwRpTLcht9CLvX/h5a7XaOaBtygoQ+aCMTPlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}