SELECT 
  product_id, 
  feature_id, 
  variant_id 
FROM 
  cscart_product_features_values 
WHERE 
  product_id IN (
    388351, 388352, 388353, 388354, 388355, 
    388356
  ) 
  AND feature_id IN (697, 1115) 
  AND lang_code = 'en'

Query time 0.00137

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "5.84"
    },
    "table": {
      "table_name": "cscart_product_features_values",
      "access_type": "range",
      "possible_keys": [
        "PRIMARY",
        "fl",
        "lang_code",
        "product_id",
        "fpl",
        "idx_product_feature_variant_id"
      ],
      "key": "lang_code",
      "used_key_parts": [
        "lang_code",
        "feature_id",
        "product_id"
      ],
      "key_length": "12",
      "rows_examined_per_scan": 12,
      "rows_produced_per_join": 12,
      "filtered": "100.00",
      "using_index": true,
      "cost_info": {
        "read_cost": "3.44",
        "eval_cost": "2.40",
        "prefix_cost": "5.84",
        "data_read_per_join": "9K"
      },
      "used_columns": [
        "feature_id",
        "product_id",
        "variant_id",
        "lang_code"
      ],
      "attached_condition": "((`webmarco`.`cscart_product_features_values`.`product_id` in (388351,388352,388353,388354,388355,388356)) and (`webmarco`.`cscart_product_features_values`.`feature_id` in (697,1115)) and (`webmarco`.`cscart_product_features_values`.`lang_code` = 'en'))"
    }
  }
}

Result

product_id feature_id variant_id
388351 697 63647
388352 697 63646
388353 697 63646
388354 697 63646
388355 697 63647
388356 697 63647
388351 1115 66095
388352 1115 66095
388353 1115 66096
388354 1115 66097
388355 1115 66096
388356 1115 66097