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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ec4e19c485f81cf0051bf885c8bf183f8a2820f8299831c857adf3b5b2552e' 
  AND token = '+vBkV9XsXoEkzkzGUvx7sFmczr8lUfYxthCZZYrmc3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}