SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5bfeea7c647a39be2ace531c01fa45a064eb5c3fa92cd39167096779675d8f' 
  AND token = 'aTCrCHg51znrDxDepG5dOKVQeWI7bBU6RIl8w6VZcdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}