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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dadd4d7070b9310d243bb927795a06f36cec1cb0a2a9e3f82b3b5eb745d81974' 
  AND token = 'ED+fDRTGa/o2SqpD7UA0C4jj1u0zDna9xxCgjCttHSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}