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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46290d4e44a4534384fe909b53f2fdcc5d194bdeeb1a884c9075ca70d114b090' 
  AND token = 'aUY3ws5T+Aqiph/4rb3Px6PNunwhO8qTR6VdUYhrlx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}