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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f66b302e56b28f34aff46ad86258937fe09d8c36d671e79a51d2a59b785e2fd4' 
  AND token = 'vvZ15SaQXpYhBb36rMiyRG3O0Wp6nsyRUc3VVxcY+x4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}