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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40728d937d47ad50ef6c17a66cc243a8c7d9973227dded175f5d822d5a4c275c' 
  AND token = 'uO+HQsdnzIuAvnBG/em0TUjg0lY9wsi+FvX0t7tusFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}