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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b373f4c691eb00dcf31aef8d1bff24229a24b498bd63b2f25a97195ea0939f0d' 
  AND token = 'A1LM+xyIwxPycGyFXdDGegbFpmKVEvE1MyYTnpL8CHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}