SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f06ddc08280b6ccb455ed5c3d0a15b2bfd47fb5875f6dc0d3122fd58121ddd5' 
  AND token = 'XE7kNmyOEVBRSIZ4fSRf33nDDIg1HNTXF9I6bbJ1DUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}