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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fc0dca35e880a3d5672ec7cb1e24da2bed4c7ad6bded20623b386344a65ce94' 
  AND token = '28WARQ0eAMmyNHE7HLafOmp5zqtCeu21UlMhpmTxRnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}