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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eac1101cb7d4a7a1363f317a5447b3538aa80e5e61218ebdb4dc124d764c856d' 
  AND token = 'g5vZSgN0b9D4RW4MphlMfGEsxmyNZj9q8lFjgMsjkUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}