SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '747994d23c5388160bbf1f0a179c3b3e03b014b806554c32fc5cf65732a7af5e' 
  AND token = '+25x47eb9UG3K4ex0cbmm+PBBm9DrkejkEnS37eo0Fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}