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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b51110bc7ab377cbdea3daaae49dce17b077010cefc222e75a2b5635126b6ad' 
  AND token = 'mJtV2IwRtdv2xs1oPrYzuC5lvEs+hs3nYoDLhWj/2ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}