SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13466d07c446fcab1166f92cb7e742939e53eb604c1555caa70cc82377a02b7c' 
  AND token = 'ioJd5t89y6aFN9RPmFyg0/3ANreedWceYpx6RQBYfcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}