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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18e353fbfea659f7d33eae5a14a62bee2301774a7ff3b6c99e46554d29afa19' 
  AND token = 'UVBa/0zfr4yEUTz9iNi7l+FJX4mDgEGFWnPk5OChHXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}