SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ff4d9deb73b2f9e15066b978c25bf0d2d3bdbc58113fb9668ed520788ed2a1' 
  AND token = 'gLDG1Q0KtU8UgCv+4VgLaHzvm3PWjxv6JAAAtdI9bEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}