SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29f266f2d20e6baaae03aadc17b4f261afe4459044d1c5936c1dde3206b9a139' 
  AND token = 'p/v0GC3uXK/vkJM0ts61USh4k1AWdwqcpcnxgQCSEo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}