SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4b7ed16bd797fa0a532294f427c6f3538bfce47c0e903abb9d4d9e8ed997c28' 
  AND token = 'ks4X64L4g7uTAO2XOahfUMwtnz8+FMyC5Rkl+AEJgbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}