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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24ec603a6e46f9afad90c247bcab7aa507f7d0e14740c3ef3e379e5f0195ce68' 
  AND token = 'G8yB9+shruBLGeR30ydWUUGS+p5APThA0HFVaRR3vIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}