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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b48d8cfc2cb22bd67009b7a7cbf752d10c270b19458db0220aeab34c2c78573f' 
  AND token = 'JLoIdjjpaoTc39nBdMOz9EVW5CmiQNAT9T0Or7pf5aE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}