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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ce299e07d2e9ac4e44cb9dbd928a576dafab34fd94c15cd2da20b98076bc630' 
  AND token = 'M5PY3DFI4WXEV7vRMG4LoWtjUE2IX3+XQGtUBeYVu7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}