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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72fa92c2956b24c66237a68f0aaba86b0bed415fb549403d1052dd05e0615498' 
  AND token = 'Ufm/HIUAVE/5Wzg8URJ2NqFx4Mj8mIPKdzv3nTaotL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}