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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3308906f47f5543958c143f8dc2670817b53538262bb254563ae221d5232e057' 
  AND token = '0Vc0/YR/HZGTRsIBfsHzK2tuCcURdiLd9sjYCXTxx1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}