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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed1df73a30f37d1b15617b75f675ff6d27eaefe86c0a907dde5e794468067c6' 
  AND token = 'ATiQz1bw53oIICUOpafg8GB1WgyhxsqJ1ejz2PyOVeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}