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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '545aa42a9598b45825670536f1f2b15f843443b12c4a0412b587e6107c361ba7' 
  AND token = 'PU+sMTYu25vO44MHMU996pdPIuNzllKgV88G+g8r3IA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}