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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e411b95f757d4bcacddd18b2a6c232abc247da1d175a3abe799fd2becd279a21' 
  AND token = 'OxXqB9uK9s9IHY3BKQfhaPrWsbhmq7samvZNaaeELkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}