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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0f25fd38c0300723cd422d41df4587153f5e3c377bd450c3b01daf8fb81023d' 
  AND token = '4sJQo9GGmv+pDlVcT+m4YUwZcPCNxbiK9x3OSWeP458=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}