SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7559e235d65b1e224fbcd36bc882438a3fa51d3a747d8be124fc8c756cf833fb' 
  AND token = '6P63fY9083N2kvMzw89BgJdBLTjqvbo7ClVGDdvrLAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}