SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17c14fa1099d8b6595b12acf7aa7976b10871a2ade46c9e52591d2c29346c09f' 
  AND token = 'qzI8ZGmoWBBOghWylS50+Kq4w1Si3HP8EwgdaMt+ksE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}