SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ecc44f412436ec4387bff13cbfd9e8e12a403db5208e80f1bcb2bbf61f356ef' 
  AND token = 'EBavI6DA6YU/17HALcqMd8qcYr3LyvqJL5iv9kvFhPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}