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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b1a1751a8b50f8d1145299e99195111885381682d29a5a9b9da0f35e1614b25' 
  AND token = '07gVpiMUEdRr82p+hxfMR6Y8sH9rZQVSQqf1zjuF0mI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}