SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdfb2b00ed6367b465604fec9d75c5411ff809bb71944991bb0d920cb0f9b689' 
  AND token = 'OrJSUiNHSExIZnBPxbFDLxuMeUjmVRp1cA+ciEfUk7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}