SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c9d139a40b955520be7855e69947dd35d07e8254bc3b4b4419c16b4226e5586' 
  AND token = 'iWKbxFuAhzrrz7Nrgqvd3ZjAxE3tABuaSpc3KHf3SCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}