SELECT 
  product_id, 
  feature_id, 
  variant_id 
FROM 
  cscart_product_features_values 
WHERE 
  product_id IN (
    432251, 432259, 432260, 432261, 432262, 
    432263, 432264, 432265, 432266
  ) 
  AND feature_id IN (860, 1013) 
  AND lang_code = 'en'

Query time 0.00139

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "8.25"
    },
    "table": {
      "table_name": "cscart_product_features_values",
      "access_type": "range",
      "possible_keys": [
        "PRIMARY",
        "fl",
        "lang_code",
        "product_id",
        "fpl",
        "idx_product_feature_variant_id"
      ],
      "key": "lang_code",
      "used_key_parts": [
        "lang_code",
        "feature_id",
        "product_id"
      ],
      "key_length": "12",
      "rows_examined_per_scan": 18,
      "rows_produced_per_join": 18,
      "filtered": "100.00",
      "using_index": true,
      "cost_info": {
        "read_cost": "4.65",
        "eval_cost": "3.60",
        "prefix_cost": "8.25",
        "data_read_per_join": "13K"
      },
      "used_columns": [
        "feature_id",
        "product_id",
        "variant_id",
        "lang_code"
      ],
      "attached_condition": "((`webmarco`.`cscart_product_features_values`.`product_id` in (432251,432259,432260,432261,432262,432263,432264,432265,432266)) and (`webmarco`.`cscart_product_features_values`.`feature_id` in (860,1013)) and (`webmarco`.`cscart_product_features_values`.`lang_code` = 'en'))"
    }
  }
}

Result

product_id feature_id variant_id
432251 860 64682
432259 860 64539
432260 860 64539
432261 860 64539
432262 860 64575
432263 860 64575
432264 860 64575
432265 860 64682
432266 860 64682
432251 1013 64581
432259 1013 64581
432260 1013 64557
432261 1013 64558
432262 1013 64581
432263 1013 64557
432264 1013 64558
432265 1013 64557
432266 1013 64558