SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e0f775eceaeeddef7b3c86ca958c132f39bb130c7cbf309be5c0e6e76af9087' 
  AND token = 'E44cQ/Q8Zam4BFGbtJmlQ3RS9mtCKpmR38PdndZng18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}