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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7441289549bed76aa0482311d91cb3952e761bb4f46e0a311c21369d8ec13eb4' 
  AND token = 'W6NhHo9hDk6Krx8OXTdD4oB233MTj45dX5RxnKUTG4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}