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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746ead7eab75e64373e0597d762d014af05c7dd33e328ebc90668b9cb521b950' 
  AND token = 'yvoTcS6+66Q68DZg8zseS2yG3DLVwxBma8WOlUkTPZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}