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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d15cb1eaf06d04e153dfc0c8183ab5125ffada5c258a100226148bbb6d975ab' 
  AND token = '81hXePL6EwnHlHzd0N6U1HBe1UfHm59ON6jL9Wfq7H4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}