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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0925dd509302a418525f5a12fe8c427c80bf9dacd7b96d092aeeee12edddd856' 
  AND token = 'X6A0uvAivIZj3zhRXx4m1e3cpM/eRR+oGUKw3ZQ7GO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}