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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ad6debc5ffbdc2104141722f9bc10857af5c322fc292561a268e49bb79f2d2e' 
  AND token = 'JcL2IkZ5gJGFFm+51C3P7rCPrGVTz/rARDHRZ4rTpN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}